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This function is used to generate a list object to be passed to getABSignal

Usage

getCorMatrix(binmat, squeeze = FALSE)

Arguments

binmat

A binned matrix list object from getBinMatrix

squeeze

Whether to squeeze the matrix for Fisher's Z transformation

Value

A list object to pass to getABSignal

Examples


library(GenomicRanges)

# Generate random genomic intervals of 1-1000 bp on chr1-22
# Modified from https://www.biostars.org/p/225520/
random_genomic_int <- data.frame(chr = rep("chr14", 100))
random_genomic_int$start <- apply(random_genomic_int, 1, function(x) {
  round(runif(1, 0, getSeqLengths(getGenome("hg19"), chr = x)[[1]]), 0)
})
random_genomic_int$end <- random_genomic_int$start + runif(1, 1, 1000)
random_genomic_int$strand <- "*"

# Generate random counts
counts <- rnbinom(1000, 1.2, 0.4)

# Build random counts for 10 samples
count.mat <- matrix(sample(counts, nrow(random_genomic_int) * 10, replace = FALSE), ncol = 10)
colnames(count.mat) <- paste0("sample_", seq(1:10))

# Bin counts
bin.counts <- getBinMatrix(
  count.mat,
  makeGRangesFromDataFrame(random_genomic_int),
  chr = "chr14",
  genome = "hg19"
)
#> 1074 bins created...

# Calculate correlations
getCorMatrix(bin.counts)
#> Calculating correlations...
#> Done...
#> $gr.cor
#> GRanges object with 96 ranges and 0 metadata columns:
#>        seqnames              ranges strand
#>           <Rle>           <IRanges>  <Rle>
#>    [1]    chr14     1000000-1099999      *
#>    [2]    chr14     6700000-6799999      *
#>    [3]    chr14     7100000-7199999      *
#>    [4]    chr14     7800000-7899999      *
#>    [5]    chr14     8600000-8699999      *
#>    ...      ...                 ...    ...
#>   [92]    chr14 101100000-101199999      *
#>   [93]    chr14 102600000-102699999      *
#>   [94]    chr14 102800000-102899999      *
#>   [95]    chr14 103800000-103899999      *
#>   [96]    chr14 106800000-106899999      *
#>   -------
#>   seqinfo: 1 sequence from an unspecified genome; no seqlengths
#> 
#> $binmat.cor
#>              [,1]         [,2]         [,3]        [,4]         [,5]
#>  [1,]  1.00000000  0.333150585 -0.577962193 -0.35931015  0.539009134
#>  [2,]  0.33315058  1.000000000  0.025061861 -0.15498568 -0.199966950
#>  [3,] -0.57796219  0.025061861  1.000000000  0.34569643 -0.364931513
#>  [4,] -0.35931015 -0.154985679  0.345696427  1.00000000 -0.390061101
#>  [5,]  0.53900913 -0.199966950 -0.364931513 -0.39006110  1.000000000
#>  [6,] -0.79730996 -0.103719956  0.308463926  0.35325546 -0.391556696
#>  [7,]  0.25338676  0.905198679  0.048386837 -0.32945552 -0.067004823
#>  [8,]  0.38231987  0.026780378  0.205749695  0.36940118  0.115542290
#>  [9,] -0.33772465 -0.186933635  0.058284245 -0.45285681 -0.156099418
#> [10,] -0.37534931 -0.415699584  0.057235818  0.16517828 -0.199278919
#> [11,]  0.10835083 -0.559104602 -0.289938751  0.32883988  0.273655481
#> [12,]  0.28513297  0.346193858  0.193046836  0.02210788 -0.315063019
#> [13,] -0.31469702 -0.095522251  0.083933876  0.41258423 -0.365292500
#> [14,]  0.40138494 -0.243670520 -0.286851688 -0.04149536  0.303891828
#> [15,]  0.66073764 -0.007162802 -0.356812292 -0.35495434  0.915515234
#> [16,]  0.35236129 -0.335124916 -0.418810939  0.07649728  0.726783324
#> [17,]  0.09746884  0.300080671 -0.260819364  0.36059023 -0.164114314
#> [18,]  0.07317073  0.333150585 -0.467874157 -0.39713227  0.000000000
#> [19,] -0.13413725  0.366440817 -0.010090720 -0.14560530 -0.175665150
#> [20,] -0.13085141  0.051066347  0.097029141  0.15363351  0.312123699
#> [21,]  0.60414045  0.145438596 -0.465445780 -0.54595438  0.439922158
#> [22,]  0.09626427 -0.578551791 -0.013034980 -0.03881220  0.482206176
#> [23,] -0.25747938 -0.338669799  0.109759684  0.29723810  0.435541057
#> [24,]  0.22447851  0.057654874  0.222126444  0.36684426 -0.118720830
#> [25,]  0.11287680  0.151733078 -0.010917467  0.16753718  0.601849234
#> [26,]  0.60335188  0.695931012 -0.258713004 -0.17776817  0.088891328
#> [27,] -0.08633789  0.047172170  0.284477726 -0.36684426  0.245921719
#> [28,] -0.42985413 -0.169619735  0.184318401  0.12664978 -0.010555008
#> [29,] -0.20546018 -0.145517881  0.633700784 -0.14868398 -0.235435478
#> [30,] -0.15491428  0.073892100  0.384572401 -0.38779444  0.282575312
#> [31,]  0.50442188  0.270888347  0.008756782 -0.17449312  0.247720179
#> [32,] -0.48634993 -0.425508209 -0.148498396  0.47469368 -0.407441634
#> [33,] -0.32337439  0.222142883  0.656813581  0.26656501 -0.016716659
#> [34,]  0.20586455  0.919459629 -0.059733782  0.05016559 -0.245527367
#> [35,] -0.29869671 -0.258048139 -0.150376188  0.46675407 -0.332871465
#> [36,]  0.00000000  0.627103203  0.266429945  0.00000000  0.217414138
#> [37,] -0.63537437 -0.168752287  0.645262154  0.17652924 -0.370536314
#> [38,]  0.12950244 -0.048044097 -0.250046131 -0.19412632 -0.007066476
#> [39,] -0.09455530  0.499398300 -0.132303571 -0.03225806 -0.120733198
#> [40,] -0.55877519 -0.205316228  0.391588129  0.40588524 -0.043328359
#> [41,]  0.02439024  0.777351364  0.412830138  0.05673318 -0.179669711
#> [42,]  0.34292247 -0.451055477 -0.197776759  0.33678910  0.299392475
#> [43,] -0.31273385 -0.348063313 -0.243101741  0.42568585 -0.307165447
#> [44,] -0.02752201 -0.275680469 -0.254658385 -0.17498214  0.162191784
#> [45,]  0.14304410  0.008683841  0.238888725  0.47469368  0.154546827
#> [46,]  0.04298541  0.104381376 -0.451095035 -0.65991202 -0.068607554
#> [47,]  0.34279520  0.266913682  0.010090720 -0.13173813  0.578231119
#> [48,]  0.21522676 -0.083994848 -0.228984532  0.03337536 -0.211394519
#> [49,] -0.22168564 -0.276635997  0.005558902  0.69135858 -0.145158930
#> [50,]  0.12895624  0.300096455 -0.378337771  0.13998134 -0.042220033
#> [51,] -0.32880508  0.099804574  0.519434214  0.68323965 -0.193770312
#> [52,] -0.03787770 -0.287432282  0.042741288  0.17621164  0.046504083
#> [53,]  0.31402432 -0.652562120 -0.288928105 -0.23598816  0.486375013
#> [54,] -0.13643902 -0.136075618  0.171553330  0.35968080  0.210586587
#> [55,]  0.66792615 -0.047703632 -0.381278198 -0.01827808  0.356959319
#> [56,]  0.25744482 -0.343833954  0.069720324  0.24751732 -0.050572174
#> [57,] -0.18157378  0.223699614  0.658052974  0.22028534 -0.110151644
#> [58,] -0.07165744  0.054376744 -0.444721319 -0.27779921 -0.263930754
#> [59,]  0.36804845  0.029399052  0.196724249  0.16521285  0.570781793
#> [60,] -0.34985827  0.048270454  0.586189827 -0.36990522 -0.234292392
#> [61,] -0.08058811 -0.334307024  0.078811041  0.34574631 -0.342997170
#> [62,] -0.16101751  0.635372437  0.641980296  0.35789039 -0.246011883
#> [63,] -0.25911712 -0.123595506  0.359220005  0.50513851 -0.290861019
#> [64,] -0.14256649 -0.021637116  0.128697890  0.25424067 -0.472594528
#> [65,]  0.12994442  0.690251917 -0.048876533 -0.38621930 -0.053179454
#> [66,] -0.54270038 -0.277981458  0.658313226  0.29454924 -0.116601906
#> [67,] -0.17460757  0.000000000  0.472866244  0.21661214  0.471621109
#> [68,] -0.12612169  0.331782748 -0.123340547  0.14342371 -0.289044049
#> [69,]  0.07935202 -0.106667861 -0.376072252 -0.53966976  0.022268319
#> [70,] -0.42150666 -0.046059462  0.026635230  0.48891771 -0.364321307
#> [71,]  0.23361262  0.181214750 -0.287040947 -0.31798791  0.101979116
#> [72,] -0.29962582  0.003637903  0.100077153  0.31037407  0.064743978
#> [73,] -0.24323744 -0.137115851  0.227417758  0.37180157 -0.392489182
#> [74,]  0.00000000 -0.313684383  0.331424894 -0.19399250  0.204786547
#> [75,]  0.16153751 -0.483321758 -0.536421956  0.16819107  0.181327128
#> [76,]  0.59865454  0.666284382 -0.247691842 -0.17019526 -0.208248282
#> [77,] -0.32666086 -0.113318540 -0.063189410  0.42695373 -0.068752387
#> [78,] -0.44823554 -0.507118411 -0.003065394 -0.25486339 -0.153422003
#> [79,] -0.14480004 -0.219760994 -0.070025447 -0.01603875  0.355554481
#> [80,]  0.41444213  0.779951346 -0.149650396 -0.29563202 -0.010176569
#> [81,]  0.27330408 -0.237022732 -0.308396977  0.09081740  0.287611871
#> [82,]  0.05950226 -0.120407668  0.000000000  0.01537843 -0.219160465
#> [83,] -0.12315869 -0.471028860 -0.116736946  0.53093283 -0.338704170
#> [84,]  0.26445343  0.416647063 -0.474613802 -0.61904027 -0.037106383
#> [85,]  0.23017684  0.435326610 -0.051946419  0.23887311 -0.426070848
#> [86,] -0.06848673  0.197488553  0.100464759  0.52039392  0.025225230
#> [87,] -0.14904416 -0.575199981 -0.254675280  0.22121852 -0.146390346
#> [88,]  0.55005683  0.190814526 -0.514282220 -0.20105885 -0.077180393
#> [89,]  0.29944952  0.381755087  0.229771693  0.43649695  0.029411765
#> [90,] -0.15373340 -0.009332761 -0.117961729  0.44341553 -0.392589820
#> [91,]  0.05521576 -0.167600381  0.186916795 -0.59936428  0.474535376
#> [92,] -0.58418691 -0.242651784  0.541236167 -0.29561036 -0.241593736
#> [93,] -0.59865454 -0.469427633  0.371537763 -0.28623748 -0.085749293
#> [94,] -0.45188205 -0.262895775 -0.263450805  0.28613413 -0.240411184
#> [95,] -0.04546394 -0.289799936 -0.123123883 -0.50760899  0.200944926
#> [96,]  0.54876666  0.620855901 -0.540418564 -0.33265436 -0.220498181
#>              [,6]         [,7]         [,8]         [,9]       [,10]
#>  [1,] -0.79730996  0.253386755  0.382319870 -0.337724646 -0.37534931
#>  [2,] -0.10371996  0.905198679  0.026780378 -0.186933635 -0.41569958
#>  [3,]  0.30846393  0.048386837  0.205749695  0.058284245  0.05723582
#>  [4,]  0.35325546 -0.329455523  0.369401175 -0.452856813  0.16517828
#>  [5,] -0.39155670 -0.067004823  0.115542290 -0.156099418 -0.19927892
#>  [6,]  1.00000000 -0.127432909 -0.494423406  0.111328943 -0.04737475
#>  [7,] -0.12743291  1.000000000 -0.136312576 -0.085729839 -0.38102737
#>  [8,] -0.49442341 -0.136312576  1.000000000 -0.081444193 -0.18348161
#>  [9,]  0.11132894 -0.085729839 -0.081444193  1.000000000  0.05784018
#> [10,] -0.04737475 -0.381027368 -0.183481606  0.057840179  1.00000000
#> [11,] -0.30359630 -0.403251691  0.212768047 -0.274845333  0.35409079
#> [12,] -0.59920160  0.402556157  0.435488971 -0.085156257  0.03953156
#> [13,]  0.42752638 -0.077732614 -0.462244883 -0.517309680 -0.01189920
#> [14,] -0.14058382 -0.443723395  0.016132705 -0.375972952 -0.22259611
#> [15,] -0.50692283  0.105604751  0.073979559 -0.445919734 -0.13740952
#> [16,] -0.13164100 -0.334149914 -0.050984342 -0.600792186  0.12701589
#> [17,] -0.01300501  0.393908568 -0.110810027 -0.474069182 -0.05212283
#> [18,] -0.04556057  0.565247377 -0.558775195  0.059598467  0.13187949
#> [19,]  0.20880513  0.564559419 -0.549915172 -0.094688927 -0.24176268
#> [20,]  0.31426489  0.188224139  0.193841243  0.118760674 -0.42762275
#> [21,] -0.40860362  0.136514311  0.005023857  0.111990592 -0.49389261
#> [22,] -0.35964011 -0.440033329 -0.060358140 -0.310497427  0.48847542
#> [23,]  0.50768758 -0.333792988  0.117286015  0.004660448 -0.24988316
#> [24,] -0.48383321  0.129713055  0.653775200 -0.194092251 -0.12209506
#> [25,]  0.18073027  0.146904777  0.143881762 -0.312594477 -0.19450125
#> [26,] -0.52126120  0.732889792  0.378304396 -0.068801261 -0.41406867
#> [27,]  0.09676664  0.339461825 -0.112432678  0.194092251 -0.45246993
#> [28,]  0.56207225 -0.212979209  0.145126430  0.574199282 -0.26818231
#> [29,] -0.09594905 -0.207976570  0.346835118  0.479736256  0.00000000
#> [30,]  0.18602825  0.307728034 -0.016010763  0.400169575 -0.52466973
#> [31,] -0.18120224  0.006201617  0.290074551 -0.233872940 -0.53257682
#> [32,]  0.24048359 -0.425243122 -0.089689306  0.191078350  0.67825429
#> [33,]  0.36561404  0.084327287  0.168280290 -0.102584427  0.04955276
#> [34,]  0.16480780  0.803774156 -0.134751773 -0.368894287 -0.42812375
#> [35,]  0.39701033 -0.271752291 -0.465440038 -0.475355465  0.19113263
#> [36,]  0.19296125  0.707578658  0.000000000 -0.192316583 -0.29461717
#> [37,]  0.23490110 -0.156557755 -0.108533733  0.168194095  0.72674180
#> [38,]  0.21502968 -0.292074443  0.010410080  0.302379833 -0.48477275
#> [39,]  0.37091823  0.661933573 -0.551821509 -0.255694663 -0.35395345
#> [40,]  0.38455154 -0.145713443 -0.290780142 -0.301822598  0.67276589
#> [41,]  0.00000000  0.721177688  0.323501428  0.099330778 -0.31448185
#> [42,] -0.17793707 -0.566357674  0.248093031 -0.614492111 -0.15847880
#> [43,]  0.42190895 -0.505391798 -0.092176973 -0.016981706  0.33241298
#> [44,]  0.02570533 -0.224338970 -0.537604041 -0.327288452  0.53801669
#> [45,] -0.32064479 -0.105167654  0.807203751 -0.135152979  0.22608476
#> [46,] -0.07025903  0.127100496 -0.352449901  0.738756393  0.07151528
#> [47,] -0.11136273  0.245357047 -0.097043854 -0.536570586 -0.16737416
#> [48,]  0.00000000 -0.407878413 -0.022244203 -0.195339698 -0.06394196
#> [49,]  0.55214010 -0.468485783  0.005940082 -0.509596519 -0.15367530
#> [50,]  0.46170220  0.075573268 -0.300619033 -0.399138525 -0.42909169
#> [51,]  0.29481716 -0.073573424  0.523335059 -0.096413692  0.13675911
#> [52,]  0.22995347 -0.302696936 -0.319704703 -0.555333416 -0.18905258
#> [53,] -0.56403095 -0.629306105  0.273788472  0.121985809  0.43202228
#> [54,]  0.21845642 -0.127725857  0.465342932  0.085729839 -0.18646020
#> [55,] -0.38531137 -0.238625875  0.255823633 -0.569635729 -0.24512553
#> [56,] -0.31258671 -0.403240967  0.509090959 -0.184528956 -0.32123523
#> [57,]  0.10973367  0.039263270  0.188028833 -0.227930899  0.19990999
#> [58,]  0.16731862 -0.057264527 -0.388813338  0.466926954  0.05960861
#> [59,] -0.43421581 -0.046440519  0.630641478 -0.299780021  0.05639845
#> [60,]  0.01980392  0.296531383 -0.115050388  0.526751439 -0.12787745
#> [61,] -0.25089541 -0.244725366  0.408119777  0.126904028  0.10055646
#> [62,]  0.10025934  0.597628475  0.297698774 -0.212755665 -0.08185421
#> [63,]  0.15557993 -0.218904256  0.607021891  0.205023987 -0.03079256
#> [64,]  0.16644489 -0.307613667  0.051571062 -0.127734386  0.29648669
#> [65,] -0.02022783  0.899982693 -0.443938383 -0.141121790 -0.27924529
#> [66,]  0.33263844 -0.075896646 -0.155414348 -0.121559949  0.01410775
#> [67,]  0.22831483  0.055814557  0.252645576 -0.113776025 -0.13072340
#> [68,]  0.39265536  0.047034982  0.070968224  0.315031548 -0.13988665
#> [69,] -0.11646506 -0.121391752 -0.483872125  0.164353009  0.45735081
#> [70,]  0.45667309 -0.115874345 -0.256154711 -0.107116586  0.17531626
#> [71,] -0.46062806  0.294555099 -0.056336993  0.054969885  0.52901456
#> [72,]  0.58208388 -0.178146210  0.135842122  0.177667629 -0.15453209
#> [73,]  0.42190895 -0.283241557 -0.259771469 -0.469827211 -0.13007465
#> [74,] -0.14393554 -0.098523413  0.244845156  0.215603926 -0.39966834
#> [75,] -0.08621410 -0.601197751 -0.127997220 -0.372167302  0.48951191
#> [76,] -0.30286661  0.502331015  0.096245934 -0.333201215 -0.58099289
#> [77,]  0.45764778 -0.231214552 -0.011253728 -0.060815843  0.32996337
#> [78,]  0.05074524 -0.349520482 -0.330834725  0.546533747  0.74008465
#> [79,]  0.27048406 -0.247962677  0.224481485  0.522312030 -0.18067901
#> [80,] -0.17418847  0.854492037 -0.259857118 -0.425335993 -0.41370703
#> [81,] -0.49229435 -0.156006430  0.423699512  0.000000000  0.38974188
#> [82,] -0.28713552 -0.158502691  0.597887687  0.630049287 -0.12374317
#> [83,]  0.20705254 -0.594465154  0.053460735 -0.292917684 -0.05122510
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#> [96,] -0.34946147  0.534225048  0.024061483  0.048761153 -0.35274569
#>             [,11]        [,12]        [,13]       [,14]        [,15]
#>  [1,]  0.10835083  0.285132974 -0.314697016  0.40138494  0.660737640
#>  [2,] -0.55910460  0.346193858 -0.095522251 -0.24367052 -0.007162802
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#>  [5,]  0.27365548 -0.315063019 -0.365292500  0.30389183  0.915515234
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#>  [7,] -0.40325169  0.402556157 -0.077732614 -0.44372340  0.105604751
#>  [8,]  0.21276805  0.435488971 -0.462244883  0.01613270  0.073979559
#>  [9,] -0.27484533 -0.085156257 -0.517309680 -0.37597295 -0.445919734
#> [10,]  0.35409079  0.039531559 -0.011899198 -0.22259611 -0.137409515
#> [11,]  1.00000000  0.217143448  0.112566631 -0.11038275  0.287534714
#> [12,]  0.21714345  1.000000000 -0.122631678 -0.41058249 -0.101151831
#> [13,]  0.11256663 -0.122631678  1.000000000  0.28248547 -0.226970108
#> [14,] -0.11038275 -0.410582491  0.282485472  1.00000000  0.313910926
#> [15,]  0.28753471 -0.101151831 -0.226970108  0.31391093  1.000000000
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#> [64,] -0.21714345  0.041666667 -0.016722502  0.16618815 -0.324145640
#> [65,] -0.20616536  0.337579789  0.177823124 -0.43066352  0.146676086
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#> [70,] -0.02353993 -0.354787438  0.597248637  0.08786415 -0.437173768
#> [71,]  0.28662962  0.434942942 -0.468876324 -0.51972107  0.266203968
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#> [73,] -0.16318572 -0.176029634  0.790711241  0.55278221 -0.255505852
#> [74,]  0.18869831  0.286135135 -0.093571285 -0.06464622  0.115772371
#> [75,]  0.49500555 -0.260785462  0.113686375  0.40508763  0.272389295
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#> [78,]  0.22929365  0.010586012 -0.264474758 -0.39862983 -0.218150044
#> [79,] -0.09189391 -0.564259306 -0.558061775 -0.11347347  0.000000000
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#> [88,] -0.15459280  0.130139310 -0.175124505  0.39333815  0.007602639
#> [89,]  0.25845240  0.490098029  0.295043942 -0.01642659  0.330280812
#> [90,]  0.19902903 -0.011981419  0.858339249  0.21926295 -0.303426329
#> [91,] -0.17520687 -0.107582871 -0.194297910  0.07572282  0.293819517
#> [92,] -0.15219867  0.137786321 -0.151471632 -0.45539227 -0.258804810
#> [93,] -0.12030860 -0.165243356 -0.362802708 -0.36260567 -0.347522080
#> [94,]  0.20552296 -0.447562544  0.547708309 -0.02065701 -0.349759850
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#> [96,] -0.16463282  0.456849277 -0.163846384 -0.11630748 -0.086880520
#>              [,16]       [,17]       [,18]       [,19]       [,20]        [,21]
#>  [1,]  0.352361294  0.09746884  0.07317073 -0.13413725 -0.13085141  0.604140446
#>  [2,] -0.335124916  0.30008067  0.33315058  0.36644082  0.05106635  0.145438596
#>  [3,] -0.418810939 -0.26081936 -0.46787416 -0.01009072  0.09702914 -0.465445780
#>  [4,]  0.076497276  0.36059023 -0.39713227 -0.14560530  0.15363351 -0.545954381
#>  [5,]  0.726783324 -0.16411431  0.00000000 -0.17566515  0.31212370  0.439922158
#>  [6,] -0.131641004 -0.01300501 -0.04556057  0.20880513  0.31426489 -0.408603618
#>  [7,] -0.334149914  0.39390857  0.56524738  0.56455942  0.18822414  0.136514311
#>  [8,] -0.050984342 -0.11081003 -0.55877519 -0.54991517  0.19384124  0.005023857
#>  [9,] -0.600792186 -0.47406918  0.05959847 -0.09468893  0.11876067  0.111990592
#> [10,]  0.127015887 -0.05212283  0.13187949 -0.24176268 -0.42762275 -0.493892606
#> [11,]  0.468106449  0.44006328  0.17026558 -0.15322864  0.16845610 -0.245907003
#> [12,] -0.430234112  0.30385461  0.19008865  0.03484722 -0.15297121 -0.178596376
#> [13,]  0.071639753  0.52590514  0.02860882  0.59788382 -0.26750012 -0.083081174
#> [14,]  0.463898652 -0.27115635 -0.53517992 -0.14716451 -0.48194990  0.554249520
#> [15,]  0.786371760 -0.01077737  0.11798886 -0.11247510  0.14106843  0.334582233
#> [16,]  1.000000000  0.04559608 -0.02349075 -0.26699347  0.08281690  0.044141124
#> [17,]  0.045596075  1.00000000  0.54304067  0.62793526  0.15153757 -0.054707813
#> [18,] -0.023490753  0.54304067  1.00000000  0.49183660  0.13085141 -0.062497288
#> [19,] -0.266993470  0.62793526  0.49183660  1.00000000 -0.02056097  0.297883556
#> [20,]  0.082816903  0.15153757  0.13085141 -0.02056097  1.00000000 -0.213948344
#> [21,]  0.044141124 -0.05470781 -0.06249729  0.29788356 -0.21394834  1.000000000
#> [22,]  0.582244730 -0.06814569 -0.17327569 -0.04941231 -0.38069664  0.121688802
#> [23,]  0.424327769 -0.19925599 -0.31469702 -0.28320813  0.74987740 -0.161275221
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#> [28,] -0.215280773 -0.37791439 -0.25791248 -0.29944476  0.67207152 -0.154203477
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#> [56,] -0.039672077 -0.01763669 -0.51488965 -0.20765809 -0.13417058  0.140730395
#> [57,]  0.006172147 -0.44999967 -0.52335973 -0.28587033 -0.23084344 -0.268210220
#> [58,] -0.310566476 -0.04090844  0.14331487  0.26272613 -0.38443553  0.489637897
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#> [60,] -0.684122385 -0.19973021  0.03180530  0.36926982  0.02437607  0.027165846
#> [61,] -0.346685209  0.34045076 -0.02686270 -0.02954697  0.03705838 -0.215675764
#> [62,] -0.313604848  0.23082914 -0.05367250  0.20334537  0.26600912 -0.308678034
#> [63,] -0.263821742 -0.14370060 -0.29613385 -0.58359093  0.50498943 -0.613371469
#> [64,] -0.027461752 -0.39880917 -0.28513297 -0.60111463 -0.39335454 -0.511435075
#> [65,] -0.208586979  0.50692285  0.75800914  0.71464592  0.14938711  0.055494689
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#> [67,]  0.302702757 -0.17942675 -0.31429363 -0.12803688  0.61558089 -0.149137497
#> [68,] -0.267234951 -0.17280354 -0.12612169 -0.18496595  0.13532625  0.050271325
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#> [70,] -0.107173930  0.46009121 -0.05058080  0.51307934 -0.15247922  0.077764603
#> [71,]  0.104998688  0.10965719  0.64892394 -0.19985503 -0.06763896 -0.305954358
#> [72,]  0.108504531 -0.30242181 -0.29962582 -0.38229665  0.55296792 -0.210877488
#> [73,]  0.060240100  0.01190242 -0.38223027  0.14014160 -0.38882077 -0.124653779
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#>              [,94]        [,95]       [,96]
#>  [1,] -0.451882054 -0.045463940  0.54876666
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#> [95,] -0.007019316  1.000000000 -0.02789762
#> [96,] -0.184856183 -0.027897624  1.00000000
#>